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Support Your Longevity Genes. Discover MAAC10!
It was believed that NAD+ molecules were too big to be effective as NAD supplements. Instead, we had to use precursors like NR. But new research suggests this might not be true anymore. A 2018 study found that NAD+ supplements in liposomes had better bioavailability and lasted longer in the body than non-liposomal supplements. In 2020, a study on mice showed that liposomal NAD+ supplements not only improved bioavailability but also raised NAD+ levels in multiple tissues, including the brain.
ChromaDex recently purchased and tested 22 NMN brands and published the results. 64% of the brands tested were fake, some containing less than 1%, NMN while others had zero content. MAAC10's NMN tested a full 10mg per capsule above the label claim topping the list of products tested. MAAC10 NMN and Resveratrol products are produced exclusively for MAAC10 in Miami Florida, in a GMP and NSF certified state-of-the-art facility that adheres to highest standards in the industry. Get what you pay for and know what you are putting in your body, buy MAAC10!
We use Pharmaceutical Grade, 99% Pure micron-sized particle Trans-Resveratrol Extract with BioPerine® for Superior Performance. (All-natural purified polygonum cuspidatum root extract)
Resveratrol is one of the most powerful naturally occurring compound that can directly turn on our longevity-genes called SIRTUINS. SIRTUINS are the NAD+ dependent longevity-genes, that when activated, for example by caloric-restriction, has been shown to extend lifespan in many animal models. Resveratrol also has a positive impact on all three major longevity pathways SIRTUINS, mTOR and AMPK.
As we age, our NAD+ levels decrease, and scientists now believe this is linked to aging. The rate of decline is greater than the body's own natural ability to replace NAD+. Studies on old mice have shown that some biomarkers of aging can actually be reversed by giving them supplements to boost NAD+ levels.
Why is NAD+ so critical?
NAD+ is important for three main functions in the body: producing energy, activating "longevity genes" called SIRTUINS, and repairing DNA. SIRTUINS cannot work without enough NAD+. NAD+ is also used to help repair broken DNA strands, which maintains the integrity of the genetic code by protecting against mutations.
What causes NAD+ levels to fall?
NAD+ levels decrease because NAD+ is used by enzymes like SIRTUINS, DNA-repair enzymes, and aggressively by ecto-enzyme CD38. CD38 is the greatest destroyer of NAD+ in the body, driven by Inflammatory cytokines and Senescent cells. Eventually, more NAD+ is used up than can be replenished, contributing to the over-all decline that is experienced with aging.
It is now clear that supporting NAD+ levels is important for promoting good health, especially as we age.
